Fragile Sites—Cytogenetic Similarity with Molecular Diversity
نویسندگان
چکیده
منابع مشابه
Similarity, diversity, and the comparison of molecular structures
Similarity is a powerful tool for compound comparison and can be seen as a good method to predict toxicity. One similarity measure and its application to complex problem solving are described. The importance of the determination of compound toxicity is a fundamental requisite for the introduction of new chemicals into daily use. However, the cost, in terms of both time and money, of an accurate...
متن کاملExperience with direct molecular diagnosis of fragile X.
The utility of the pfxa3 probe for direct molecular diagnosis of the fragile X (FRAXA) has been established. This probe detects amplification of an unstable DNA element consisting of variable length CCG repeats. The size of the amplified fragment is correlated with phenotype and was determined using PstI digested DNA in family members. In 35 families with the fragile X, there was correspondence...
متن کاملassessing geopedological soil mapping using diversity and similarity indices
abstract geopedology is a systematic approach of geomorphic analysis for soil mapping which focuses the field operation mainly on sample area. the purpose of this study is to determine the credibility of generalization of the results of geopedological approach for similar landforms in the borujen region, using diversity and similarity indices in a soil taxonomic hierarchical structure. after a ...
متن کاملMolecular mechanisms of fragile X syndrome.
Fragile X syndrome is the most common form of inherited mental retardation Mutations which abolish expression of an X-linked gene, FMR1, result in pathogenesis of the disease. FMR1 encodes a cytoplasmic RNA-binding protein which interacts with two autosomal homologs, FXR1 and FXR2. These proteins are highly expressed in neurons. In addition, the FMR1/FXR proteins are associated with ribosomes. ...
متن کاملHigher abundance and diversity in faunal assemblages with the invasion of Codium fragile ssp. fragile in eelgrass meadows
The present study examined how species-specific attributes of the invasive alga Codium fragile ssp. fragile (hereafter Codium) and eelgrass Zostera marina influenced faunal assemblages associated with eelgrass ecosystems in îles de la Madeleine, eastern Canada. Direct association of species with Codium (<1 m) was evaluated and compared to eelgrass faunal assemblages from invaded beds. Potential...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 1999
ISSN: 0002-9297
DOI: 10.1086/302267